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    Antimicrobial Therapy and Vaccines

Volume II: Antimicrobial Agents


Introduction Chapters

Antibacterial Agents: Pharmacokinetic and Pharmacodynamic Issues in the Treatment of Bacterial Infectious Diseases.

Antimycobacterial Agents: Pharmacokinetic and Pharmacodynamic Issues in the Treatment of Mycobacterial Infections.

Antifungal Agents: In Vitro Susceptibility Testing, Pharmacodynamics, and Prospects for Combination Therapy.

Antiviral Agents: Optimizing Clinical Pharmacodynamics of HIV-1 Protease Inhibitors with Inhibitory Quotients

Antiparasitic Agents: Pharmacokinetic and Pharmacodynamic Issues in the Treatment of Parasitic Infections




Abacavir  [Abacavir Summary]                         

Abelcet  [Amphotericin B Summary]                   

Achromycin® [Tetracycline Summary]              

Actimmune®  [Interferons Summary]

Acyclovir [Acyclovir summary]

Adefovir   [Adefovir summary]

Agenerase® [Amprenavir summary]

Albendazole [Albendazole summary]

Albenza® [Albendazole summary]

Alferon®  [Interferons Summary]

Amantadine [Amantadine summary]

Amantadine, Rimantadine, and Related Agents  [Amantadine summary] [Rimantadine Summary]

Ambisome®  [Amphotericin B Summary]

Amikacin [Amikacin Summary]

Amikin® [Amikacin Summary]

Aminoglycoside Class [Amikacin Summary] [Gentamicin Summary] [Tobramycin Summary] [Aztreonam Summary]

4-Aminoquinolines (Amodiaquine, Chloroquine) [Amodiaquine summary] [Chloroquine summary]

Amodiaquine [Amodiaquine summary]

Amoxicillin  [Amoxicillin Summary]

Amoxicillin/Clavulanate [Amoxicillin/Clavulanate Summary]

Amoxil®  [Amoxicillin Summary]

Amphocil®  [Amphotericin B Summary]

Amphotec®  [Amphotericin B Summary]

Amphotericin B  [Amphotericin B Summary]

Ampicillin [Ampicillin Summary]

Ampicillin/Sulbactam  [Ampicillin/Sulbactam Summary]

Amprenavir [Amprenavir summary]

Ancef® [Cefazolin Summary]

Ancobon® [Flucytosine Summary]

Ancotil® [Flucytosine Summary]

Anidulafungin [Anidulafungin Summary

Ansamycin for Mycobacterial Infections  [Rifabutin for Myco Summary]

Anspor® [Cephradine Summary]

Antimonials (Meglumine antimoniat, Sodium stibogluconate)  [Antimonials summary]

Arsobal®   [Melarsoprol summary]

Atazanavir [Atazanavir summary]

Arteether [Arteether summary]

Artemether [Artemether summary]

Artemisinin [Artemisinin summary]

Artemisinin and Its Derivatives  [Arteether summary] [Artemether summary] [Artemisinin summary] [Artesunate summary] [Dihydroartemisinin summary]

Artesunate [Artesunate summary]

Atovaquone  [Atovaquone summary]

Atovaquone-Proguanil [Atovaquone Summary] [Proguanil Summary]

Augmentin® [Amoxicillin/Clavulanate Summary]

Avelox® [Moxifloxacin Summary]

Avonex®  [Interferons Summary]

Azactam®  [Aztreonam Summary]

Azithromycin [Azithromycin Summary]

Azlin® [Azlocillin Summary]

Azlocillin [Azlocillin Summary]

Azole Class (Clotrimazole, Fluconazole, Itraconazole, Ketoconazole, Miconazole, Voriconazole) [Clotrimazole Summary] [Fluconazole Summary] [Itraconazole Summary] [Ketoconazole Summary] [Miconazole Summary] [Voriconazole Summary]

Aztreonam  [Aztreonam Summary]


Bacampicillin [Bacampicillin Summary]

Bactocill® [Oxacillin Summary]

Bactrim® [Trimethoprim-Sulfamethoxazole Summary]

Bactroban®  [Mupirocin Summary]

Beta-lactam and Beta-lactamase Inhibitor Combinations (Amoxicillin/Clavulanate, Ampicillin/Sulbactam, Ticarcillin/Clavulanate,  Piperacillin/Tazobactam) [Amoxicillin/Clavulanate Summary] [Ampicillin/Sulbactam Summary] [Piperacillin/Tazobactam Summary] [Ticarcillin/Clavulanate Summary]

Benzimidazole Class (Albendazole, Mebendazole, Thiabendazole, Triclabendazole) [Albendazole summary]


Betaseron®  [Interferons Summary]


Biaxin® [Clarithromycin Summary]

Bilitricide®  [Praziquantel summary]



Canesten® [Clotrimazole Summary]

Cancidas® [Caspofungin summary]

Carbapenem Class (Biapenem, Ertapenem, Faropenem, Imipenem, Meropenem, Panipenem)  [Ertapenem Summary] [Imipenem Summary] Meropenem Summary]

Carbenecillin [Carbenecillin Summary]

Caspofungin [Caspofungin summary]

Ceclor® [Cefaclor Summary]

Cedax® [Ceftibuten Summary]

Cefaclor [Cefaclor Summary]

Cefadroxil [Cefadroxil Summary]

Cefamandole [Cefamandole Summary]

Cefazolin [Cefazolin Summary]

Cefdinir [Cefdinir Summary]

Cefditoren [Cefditoren Summary]

Cefepime [Cefepime Summary]

Cefixime [Cefixime Summary]

Cefizox® [Ceftizoxime Summary]

Cefmetazole [Cefmetazole Summary]

Cefoperazone [Cefoperazone Summary]

Cefotan® [Cefotetan Summary]

Cefotaxime [Cefotaxime Summary]

Cefotetan [Cefotetan Summary]

Cefoxitin [Cefoxitin Summary]

Cefpodoxime [Cefpodoxime Summary]

Cefprozil [Cefprozil Summary]

Ceftaz® [Ceftazidime Summary]

Ceftazidime [Ceftazidime Summary]

Ceftibuten [Ceftibuten Summary]

Ceftin® [Cefuroxime Summary]

Ceftizoxime [Ceftizoxime Summary]

Ceftriaxone [Ceftriaxone Summary]

Cefuroxime [Cefuroxime Summary]

Cefzil® [Cefprozil Summary]

Cephalexin [Cephalexin Summary]

Cephalosporin Class [Cefaclor Summary] [Cefadroxil Summary] [Cefamandole Summary] [Cefazolin Summary] [Cefdinir Summary] [Cefditoren Summary] [Cefepime Summary] [Cefixime Summary] [Cefmetazole Summary] [Cefoperazone Summary] [Cefotaxime Summary] [Cefotetan Summary]  [Cefoxitin Summary] [Cefpodoxime Summary] [Cefprozil Summary] [Ceftazidime Summary] [Ceftibuten Summary] [Ceftizoxime Summary] [Ceftriaxone Summary] [Cefuroxime Summary] [Cephalexin Summary] [Cephradine Summary] [Loracarbef Summary] [Moxalactam Summary]

Cephobid® [Cefoperazone Summary]

Cephradine [Cephradine Summary]

Ceptaz® [Ceftazidime Summary]

Cethromycin [Cethromycin Summary]

Chloproquanil [Chlorproguanil summary]

Chloramphenicol  [Chloramphenicol Summary

Chloromycetin® [Chloramphenicol Summary

Chloroquine [Chloroquine summary]

Cidofovir  [Cidofovir summary]

Cipro®  [Ciprofloxacin Summary]

Ciprofloxacin  [Ciprofloxacin Summary]

Claforan® [Cefotaxime Summary]

Clarithromycin [Clarithromycin Summary]

Cleocin® [Clindamycin Summary

Clindamycin [Clindamycin Summary

Clotrimazole [Clotrimazole Summary]

Cloxacillin [Cloxacillin Summary]

Colistin [Colistin Summary]

Colymycin® [Colistin Summary]

Copegus®  [Ribavirin summary]

Cotrimoxazole [Trimethoprim-Sulfamethoxazole Summary]

Crixivan® [Indinavir summary]

Cubicin®   [Daptomycin Summary

Cycloserine [Cycloserine Summary

Cytovene®  [Ganciclovir Summary]


Dalbavancin [Dalbavancin Summary

Dapsone [Dapsone summary]

Daptomycin   [Daptomycin Summary

Daraprim® [Pyrimethamine summary]

Darunavir [Darunavir Summary]

Declomycin®  [Demeclocycline Summary]

Delavirdine [Delavirdine summary]

Demeclocycline  [Demeclocycline Summary]

Denavir® [Penciclovir Summary]

Diclocil® [Dicloxacillin Summary]

Dicloxacillin [Dicloxacillin Summary]

Didanosine [Didanosine summary]

Diethylcarbamazine  [Diethylcarbamazine summary]

Diflucan® [Fluconazole Summary]

Diloxanide Furoate

Dihydroartemisinin [Dihydroartemisinin summary]

Doxycycline  [Doxycycline Summary]

Duricef® [Cefadroxil Summary]

Dycill® [Dicloxacillin Summary]

Dynapen® [Dicloxacillin Summary]


E-Mycin® [Erythromycin Summary]

Echinocandin Class (Anidulafungin, Caspofungin, Micafungin)  [Anidulafungin Summary]  [Caspofungin summary] [Micafungin Summary]  

Efavirenz [Efavirenz summary]

Eflornithine  [Eflornithine Summary]

Emetine and Dehydroemetine  

Emtricitabine [Lamivudine summary]

Emtriva® [Lamivudine summary]

Enfuvirtide and Other Fusion Inhibitors [Enfuvirtide summary]


Epivir® [Emtricitabine summary]

Eraxis® [Anidulafungin Summary

Ertapenem [Ertapenem Summary]

Erythromycin [Erythromycin Summary]

Ethambutol  [Ethambutol Summary]

Ethionamide [Ethionamide Summary]


Factive® [Gemifloxacin Summary]

Famciclovir [Famciclovir summary]

Famvir® [Famciclovir summary]

Fansidar® [Pyrimethamine summary] [Sulfadoxine summary]

Fansimef® [Pyrimethamine summary]


Floxin® [Ofloxacin Summary

Fluconazole [Fluconazole Summary]

Flucytosine [Flucytosine Summary]

Flumadine® [Rimantadine Summary]

Flagyl®  [Metronidazole Summary]

Folate Antagonists  [Chlorproguanil summary] [Dapsone summary] [Proguanil summary] [Pyrimethamine summary] [Sulfadoxine summary] [Trimetrexate summary]

Fortaz® [Ceftazidime Summary]

Fortovase® [Saquinavir summary]

Fosfomycin  [Fosfomycin Summary

Fucicort®  [Fusidic Acid Summary

Fucidin®  [Fusidic Acid Summary

Fungizone®  [Amphotericin B Summary]

Fungoral® [Ketoconazole Summary]

Funguard® [Micafungin Summary]

Furadantin®  [Nitrofurantoin Summary]


Fusidic Acid  [Fusidic Acid Summary

Fuzeon® [Enfuvirtide summary]


Ganciclovir  [Ganciclovir Summary]

Garamycin® [Gentamicin Summary]

Gatifloxacin [Gatifloxacin Summary]

Gemifloxacin [Gemifloxacin Summary]

Gentamicin [Gentamicin Summary]

Geocillin® [Carbenecillin Summary]

Geopen® [Carbenecillin Summary]

Glucantime® [Antimonials summary]

Glycopeptide Class (Dalbavancin, Oritavancin, Teicoplanin, Telavancin, Vancomycin)  [Dalbavancin Summary] [Oritavancin Summary] [Teicoplanin Summary] [Telavancin Summary] [Vancomycin Summary]


Halofantrine  [Halofantrine summary]

Hepsera®   [Adefovir summary]

Hetrazan®  [Diethylcarbamazine summary]

Hivid® [Zalcitabine summary]

Ilosone® [Erythromycin Summary]

Imipenem [Imipenem Summary]

Indinavir [Indinavir summary]


Influenza Neuraminidase Inhibitors (Oseltamivir and Zanamivir) [Oseltamivir summary] [Zanamivir summary]

Interferons  [Interferons Summary]

Intron®  [Interferons Summary]

Invanz® [Ertapenem Summary]

Invirase® [Saquinavir summary]


Isoniazid (INH)  [Isoniazid Summary]

Itraconazole [Itraconazole Summary]

Ivermectin  [Ivermectin summary]


Josamycin [Josamycin Summary]


Kaletra® [Lopinavir/ritonavir summary]

Keflex® [Cephalexin Summary]

Kefzol® [Cefazolin Summary]

Ketek® [Telithromycin Summary]

Ketoconazole [Ketoconazole Summary]

Ketolides (Telithromycin, Cethromycin) [Cethromycin Summary] [Telithromycin Summary]


Lamivudine [Emtricitabine summary]

Lapdap® [Chlorproguanil summary] [Dapsone summary]

Lapudrine® [Chlorproguanil summary]


Levaquin® [Levofloxacin Summary]

Levofloxacin [Levofloxacin Summary]

Lifurox® [Cefuroxime Summary]

Linezolid and Other Oxazolidinones  [Linezolid Summary

Lopinavir/ritonavir [Lopinavir/ritonavir summary]

Lorabid® [Loracarbef Summary]

Loracarbef [Loracarbef Summary]

Lotrimin® [Clotrimazole Summary] [Miconazole Summary]


Macrodantin®  [Nitrofurantoin Summary]

Macrolides Class [Azithromycin Summary] [Clarithromycin Summary] Erythromycin Summary] [Josamycin Summary] [Rokitamycin Summary] [Roxithromycin Summary]

Malarone®  [Atovaquone summary]

Maloprim® [Pyrimethamine summary]

Maloprim® [Dapsone summary]

Mandol® [Cefamandole Summary]

Maraviroc® [Maraviroc Summary]

Maxpime® [Cefepime Summary]


Mectizan®  [Ivermectin summary]

Mefloquine  [Mefloquine summary]

Mefoxin® [Cefoxitin Summary]

Meglumine antimoniat [Antimonials summary]

Melarsoprol   [Melarsoprol summary]

Mepron®  [Atovaquone summary]

Meropenem [Meropenem Summary]

Merrem® [Meropenem Summary]

Methicillin [Methicillin Summary]


Metronidazole  [Metronidazole Summary]

Mezlin® [Mezlocillin Summary]

Mezlocillin [Mezlocillin Summary]

Micafungin [Micafungin Summary]

Miconazole [Miconazole Summary]

Microsulfon®  [Sulfadiazine Summary]

Minocin® [Minocycline Summary]

Minocycline [Minocycline Summary]

Monistat® [Miconazole Summary]

Monuril®  [Fosfomycin Summary

Monurol®  [Fosfomycin Summary

Moxalactam [Moxalactam Summary]

Moxam® [Moxalactam Summary]

Moxifloxacin [Moxifloxacin Summary]

Mupirocin  [Mupirocin Summary]

Mycamine® [Micafungin Summary]

Mycobutin for Mycobacterial Infections  [Rifabutin for Myco Summary]

Mycostatin® [Nystatin Summary]


Nafcillin [Nafcillin Summary]

Nebcin® [Tobramycin Summary]

Nelfinavir [Nelfinavir summary]

Neutrexin [Trimetrexate summary]

Nevirapine [Nevirapine summary]




Nitrofurantoin  [Nitrofurantoin Summary]

Nizoral® [Ketoconazole Summary]

Nonnucleoside Analogues (Delavirdine, Efavirenz, Etravirine, Nevirapine)  [Delavirdine summary] [Efavirenz summary] [Nevirapine summary]

Norfloxacin [Norfloxacin Summary]

Noroxin® [Norfloxacin Summary]

Norvir® [Ritonavir summary]

Notezine®  [Diethylcarbamazine summary]

Nucleoside Analogues (Acyclovir, Famciclovir, Penciclovir, Valacyclovir) [Acyclovir summary] [Famciclovir summary] [Penciclovir Summary] [Valacyclovir summary]

Nucleoside Analog Reverse Transcriptase Inhibitors (Didanosine, Zalcitabine, Zidovudine) [Didanosine summary] [Zalcitabine summary] [Zidovudine summary]

Nystatin [Nystatin Summary]


Ofloxacin [Ofloxacin Summary

Oflox® [Ofloxacin Summary

Omnicef® [Cefdinir Summary]

Orbenin® [Cloxacillin Summary]

Oritavancin [Oritavancin Summary]

Oseltamivir [Oseltamivir summary]

Oxacillin [Oxacillin Summary]



Paidocin® [Rokitamycin Summary]

Paludrine® [Proguanil summary]

PALUTHER® [Artemether summary]


Panmycin® [Tetracycline Summary]

Para-Aminosalicyclic Acid  

Peg-Intron®  [Interferons Summary]

Pegasys®  [Interferons Summary]

Penciclovir [Penciclovir Summary]

Penglobe® [Bacampicillin Summary]

Penicillin [Penicillin Summary]

Penicillin Class  [Amoxicillin Summary] [Ampicillin Summary] [Azlocillin Summary] [Bacampicillin Summary] [Carbenecillin Summary] [Cloxacillin Summary] [Dicloxacillin Summary] [Methicillin Summary] [Mezlocillin Summary] [Nafcillin Summary] [Oxacillin Summary] [Penicillin Summary] [Piperacillin Summary] [Ticarcillin Summary]


Pentostam® [Antimonials summary]

Piperacillin [Piperacillin Summary]

Piperacillin/Tazobactam [Piperacillin/Tazobactam Summary]


Piperazine: Diethylcarbamazine  [Diethylcarbamazine summary]

Pipracil® [Piperacillin Summary]

PLASMOTRIM® [Artesunate summary]

Polymyxins [Colistin Summary]

Praziquantel  [Praziquantel summary]

Primaquine   [Primaquine summary]

Primaxin® [Imipenem Summary]

Proguanil [Proguanil summary]

Prostaphlin® [Oxacillin Summary]

Protease Inhibitors (Amprenavir, Atazanavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir, Saquinavir) [Amprenavir summary] [Atazanavir summary] [Indinavir summary] [Lopinavir/ritonavir summary] [Nelfinavir summary] [Ritonavir summary] [Saquinavir summary]

Pyrantel Pamoate  


Pyrimethamine [Pyrimethamine summary]

Pyrvinium Pamoate  



Quinine and Quinidine  [Quinine and Quinidine summary]

Quinolones Class  [Ciprofloxacin Summary] [Gatifloxacin Summary] [Gemifloxacin Summary] [Levofloxacin Summary] [Moxifloxacin Summary] [Norfloxacin Summary] [Ofloxacin Summary

Quinupristin/Dalfopristin  [Quinupristin/Dalfopristin Summary]


Raltegravir [Raltegravir summary]

Rebetol®  [Ribavirin summary]

Rebif®  [Interferons Summary]

Relenza® [Zanamivir summary]

Rescriptor® [Delavirdine summary]

Retrovir® [Zidovudine summary]

Reyataz® [Atazanavir summary]

Ribasphere®  [Ribavirin summary]

Ribavirin  [Ribavirin summary]

Rifabutin for Mycobacterial Infections  [Rifabutin for Myco Summary]

Rifadin for Mycobacterial Infections [Rifampin for Myco Summary]

Rifadin for Non-Mycobacterial Infection [Rifampin for NonTB Summary]

Rifampin for Mycobacterial Infections [Rifampin for Myco Summary]

Rifampin for Non-Mycobacterial Infection [Rifampin for NonTB Summary]

Rifamycins for Mycobacterial Infections  [Rifabutin for Myco Summary] [Rifampin for Myco Summary]

Rifamycins for Non-Mycobacterial Infections  [Rifabutin for NonTB Summary] [Rifampin for NonTB Summary] [Rifaximin Summary]

Rifaximin  [Rifaximin Summary]


Rimantadine [Rimantadine Summary]

Ritonavir [Ritonavir summary]

Rocephin® [Ceftriaxone Summary]

Roferon®  [Interferons Summary]

Rokital® [Rokitamycin Summary]

Rokitamycin [Rokitamycin Summary]

Roxithromycin [Roxithromycin Summary]

Rulid® [Roxithromycin Summary]


Saquinavir [Saquinavir summary]

Securopen® [Azlocillin Summary]

Septra® [Trimethoprim-Sulfamethoxazole Summary]

Seromycin [Cycloserine Summary

Sodium stibogluconate [Antimonials summary]

Spectracef® [Cefditoren Summary]

Sporanox® [Itraconazole Summary]

Staphcillin® [Methicillin Summary]

Stavudine [Stavudine summary]

Stromectol®  [Ivermectin summary]

Sulfadiazine  [Sulfadiazine Summary]

Sulfadoxine [Sulfadoxine summary]

Sulfonamides  [Sulfadiazine Summary] [Sulfonamides Summary]

Sulperazone® [Cefoperazone Summary]

Suprax® [Cefixime Summary]

Suramin  [Suramin summary]

Sustiva® [Efavirenz summary]

Symmetral® [Amantadine summary]

Synercid®  [Quinupristin/Dalfopristin Summary]


Tamiflu® [Oseltamivir summary]

Targocid® [Teicoplanin Summary

Tarivid® [Ofloxacin Summary

Tazidime® [Ceftazidime Summary]

Teicoplanin [Teicoplanin Summary

Telavancin [Telavancin Summary

Telithromycin [Telithromycin Summary]

Tenofovir  [Tenofovir summary]

Tequin® [Gatifloxacin Summary]

Tetracycline [Tetracycline Summary]

Tetracyclines and Analogues  [Demeclocycline Summary] [Doxycycline Summary] [Minocycline Summary] [Tetracycline Summary]


Ticar® [Ticarcillin Summary]

Ticarcillin [Ticarcillin Summary]

Ticarcillin/Clavulanate [Ticarcillin/Clavulanate Summary]

Tienam® [Imipenem Summary]

Tigecycline [Tigecycline Summary]

Timentin® [Ticarcillin/Clavulanate Summary]

Tipranavir [Tipranavir summary]

Tobramycin [Tobramycin Summary]


Trimethoprim [Trimethoprim Summary]

Trimethoprim-Sulfamethoxazole [Trimethoprim-Sulfamethoxazole Summary]

Trimetrexale [Trimetrexate summary]

Tygacil® [Tigecycline Summary]


Unasyn®  [Ampicillin/Sulbactam Summary]

Unipen® [Nafcillin Summary]


Valacyclovir [Valacyclovir summary]



Valtrex® [Valacyclovir summary]

Vancomycin [Vancomycin Summary]

Vantin® [Cefpodoxime Summary]

Velosef® [Cephradine Summary]

VFEND® [Voriconazole Summary]

Vibramycin®  [Doxycycline Summary]


Videx® [Didanosine summary]

Viracept® [Nelfinavir summary]

Viramune® [Nevirapine summary]

Virazole®  [Ribavirin summary]

Viread®  [Tenofovir summary]

Vistide®  [Cidofovir summary]

Voriconazole [Voriconazole Summary]


Xifaxan®  [Rifaximin Summary]


Zalcitabine [Zalcitabine summary]

Zanamivir [Zanamivir summary]

Zefazone® [Cefmetazole Summary]

Zentel® [Albendazole summary]

Zerit® [Stavudine summary]

Ziagen®  [Abacavir Summary]

Zidovudine [Zidovudine summary]

Zinacef® [Cefuroxime Summary]

Zinnat® [Cefuroxime Summary]

Zithromax® [Azithromycin Summary]

Zosyn® [Piperacillin/Tazobactam Summary]

Zovirax® [Acyclovir summary]

Zyvox®  [Linezolid Summary

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