|
Borrelia burgdorferi
(Lyme Disease)
Read the Chapter
Sliding Table of
Contents on the left of the screen
Tables and
Figures
Table 1:
Antimicrobial Treatment of Lyme Disease [Download
PDF]
Figure
1: Erythema multiforme with central clearing originating in the submammary fold.
Often there is a central area of erythema remaining at
the site of the tick bite (punctum). Although
this is the “classical” presentation of erythema migrans, it is not the most
common (See Figures 2 and
3).
Figure 2: Erythema migrans with homogenous
erythema (and lack of central clearing). Note that this is the most common
presentation of erythema migrans in the U.S.
Figure 3: Erythema migrans rash without central
clearing. Note the easily observed central punctum (arrow) at the site of tick
bite.
Figure 4: Vesicular rash surround by erythema
occurring over the knee. This lesion was thought to represent a spider bite
reaction and the patient was treated with cephalexin without response.
Borrelia burgdorferi was isolated by culture of a skin biopsy of the leading
margin of erythema.
Video
Video: Borrelia burgdorferi. Provided by
CytoViva.
Vignettes
Guideline: Halperin JJ, et al.
Practice Parameter: Treatment of Nervous System Lyme Disease (an
evidence-based review). Report of the Quality Standards Subcommittee of the
American Academy of Neurology (Endorsed by IDSA). Neurology
2007;69:91-102.
Review Article: Auwaerter PG.
Point: Antibiotic Therapy Is Not the Answer for Patients with Persisting
Symptoms Attributable to Lyme Disease. Clin Infect Dis
2007;45:143-148.
Review Article:
Stricker RB.
Counterpoint: Long-Term
Antibiotic Therapy Improved Persistent Symptoms Associated with Lyme
Disease. Clin Infect Dis 2007;45:149-157.
Dixon B.
Lyme Disease -- The Public Dimension. Microbe 2007;2:114-115.
Berger S.
Emergence of Infectious Diseases into the
21st Century, 2008.
Vazquez M, Muehlenbein C, et al.
Effectiveness of Personal Protective Measures to Prevent
Lyme Disease. Emerg Infect Dis 2008;14(2):210-216.
Steere AC et
al.
Prospective Study of Serologic Tests for Lyme Disease.
Clin
Infect Dis.
2008 Jul 15;47(2):188-95
Hingwe, A.
Jarisch-Herxheimer reaction.
2009
Authors
 Eugene
D. Shapiro, M.D., Paul Auwaerter, M.D.
Previous author: David L. Coleman, M.D., 1997
Edition, 2002 Edition
|
www.antimicrobe.org