Different erythromycin resistance mechanisms in group C and group G streptococci

Antimicrob Agents Chemother. 1998 Jun;42(6):1493-4. doi: 10.1128/AAC.42.6.1493.

Abstract

Different mechanisms of erythromycin resistance predominate in group C and G streptococcus (GCS and GGS, respectively) isolates collected from 1992 to 1995 in Finland. Of the 21 erythromycin-resistant GCS and 32 erythromycin-resistant GGS isolates, 95% had the mefA or mefE drug efflux gene and 94% had the ermTR methylase gene, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins*
  • Drug Resistance, Microbial / genetics
  • Erythromycin / pharmacology*
  • Methyltransferases / genetics
  • Phenotype
  • Streptococcus / drug effects*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Erythromycin
  • ErmTR protein, bacteria
  • Methyltransferases