A nosocomial outbreak due to Enterobacter cloacae strains with the E. hormaechei genotype in patients treated with fluoroquinolones

J Clin Microbiol. 1997 Apr;35(4):1008-10. doi: 10.1128/jcm.35.4.1008-1010.1997.

Abstract

During a 7-month period, we isolated 21 highly fluoroquinolone-resistant Enterobacter cloaecae strains in units from two hospitals in Marseille, France. Random amplification of polymorphic DNA showed clonal identity between isolates which, furthermore, presented the Enterobacter hormaechei genotype on DNA-DNA hybridization. The emergence of this clone was observed only in patients treated with fluoroquinolones.

MeSH terms

  • Cross Infection
  • Disease Outbreaks
  • Drug Resistance, Microbial*
  • Enterobacter cloacae / drug effects
  • Enterobacter cloacae / genetics
  • Enterobacter cloacae / isolation & purification*
  • Enterobacteriaceae Infections / epidemiology
  • Enterobacteriaceae Infections / microbiology*
  • France
  • Humans
  • Quinolones / pharmacology*

Substances

  • Quinolones