Long-term effects of ceftriaxone treatment on intraocular Lyme borreliosis

Am J Ophthalmol. 1993 Nov 15;116(5):571-5. doi: 10.1016/s0002-9394(14)73198-8.

Abstract

Twelve patients with intraocular Lyme borreliosis suffering from vitreitis were treated with ceftriaxone intravenously. Eight patients had definitive Lyme borreliosis, and tentative diagnosis was made in four patients. After treatment with ceftriaxone, all 12 patients were followed up for more than one year. Vitreitis diminished in all patients and visual acuity improved in six patients. The best results were achieved in patients with definitive Lyme borreliosis.

MeSH terms

  • Adult
  • Antibodies, Bacterial / immunology
  • Borrelia burgdorferi Group / immunology
  • Ceftriaxone / therapeutic use*
  • Eye Diseases / drug therapy
  • Eye Diseases / microbiology
  • Eye Infections, Bacterial / drug therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Immunoglobulin G / analysis
  • Infusions, Intravenous
  • Longitudinal Studies
  • Lyme Disease / drug therapy*
  • Lyme Disease / immunology
  • Male
  • Middle Aged
  • Treatment Outcome
  • Visual Acuity
  • Vitreous Body / drug effects
  • Vitreous Body / microbiology*

Substances

  • Antibodies, Bacterial
  • Immunoglobulin G
  • Ceftriaxone