Abstract
A 79-year-old female developed endocarditis and meningitis due to an ampicillin-resistant, non-beta-lactamase-producing strain of Haemophilus influenzae. Carbenicillin and gentamicin therapy resulted in bacteriological and clinical cure. The mechanism of resistance of ampicillin-resistant, non-beta-lactamase-producing strains of H. influenzae is unknown.
MeSH terms
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Aged
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Ampicillin / pharmacology*
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Chloramphenicol / therapeutic use
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Female
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Haemophilus Infections / blood
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Haemophilus Infections / cerebrospinal fluid
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Haemophilus Infections / drug therapy
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Haemophilus influenzae / drug effects*
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Haemophilus influenzae / isolation & purification
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Humans
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Microbial Sensitivity Tests
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Penicillin Resistance
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beta-Lactamases / analysis*
Substances
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Chloramphenicol
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Ampicillin
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beta-Lactamases