Abstract
Isolates of Microsporum canis, Microsporum gypseum and Epidermophyton floccosum were observed to produce antibacterial activities under cross-resistance to fusidic acid. The activity from E. floccosum was shown to be due to fusidic acid, diketofusidic acid and 3-ketofusidic acid. Possible contributions of these antibiotics to microbial interaction during dermatophytosis is discussed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / isolation & purification*
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Arthrodermataceae / growth & development*
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Chromatography, High Pressure Liquid
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Fermentation
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Fusidic Acid / analogs & derivatives*
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Fusidic Acid / toxicity
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Magnetic Resonance Spectroscopy
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Microsporum / growth & development*
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Spectrophotometry, Infrared
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Structure-Activity Relationship
Substances
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Anti-Bacterial Agents
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Fusidic Acid