Effect of ciprofloxacin on carrier rate of Neisseria meningitidis in army recruits in Finland

Antimicrob Agents Chemother. 1987 Jun;31(6):962-3. doi: 10.1128/AAC.31.6.962.

Abstract

The efficacy of ciprofloxacin in eradicating pharyngeal colonization of Neisseria meningitidis was studied among army recruits in Finland. Ciprofloxacin (250 mg) or placebo was given twice a day for 2 days to 118 meningococcal carriers. Meningococcal carriage was eradicated in 96% of subjects given ciprofloxacin and in 13% of those given placebos.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carrier State / drug therapy*
  • Carrier State / microbiology
  • Ciprofloxacin / therapeutic use*
  • Finland
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Military Personnel
  • Neisseria meningitidis* / drug effects
  • Pharynx / microbiology

Substances

  • Ciprofloxacin