The control of syphilis in Bosnia was organised and started by Professor Ernest Grin in 1948 and continued to the end of 1951. Regardless of the clinical picture, the treatment of endemic syphilis consisted of an oil suspension of penicillin with aluminium monostearate (PAM) 3.6 to 4.2 MIU for adults in six or seven intramuscular injections of 0.6 MIU every day or 1.2 MIU every other day. Today endemic syphilis in Yugoslavia is only historic fact.