Susceptibility to fusidic acid among Danish Staphylococcus aureus strains and fusidic acid consumption

J Antimicrob Chemother. 1990 Feb:25 Suppl B:7-14. doi: 10.1093/jac/25.suppl_b.7.

Abstract

A total of 8176 Danish Staphylococcus aureus strains isolated from cases of bacteraemia during the years 1963 to 1987 were investigated for resistance to fusidic acid. During the whole period 1% of the strains or less were resistant (MIC of 2 mg/l or more). The total Danish consumption of fusidic acid during the same period increased from 0.008 to 0.029 defined daily doses/1000 inhabitants/day. The resistant strains were mainly sporadic isolates with the phage-types and antibiotic-resistance patterns predominant in Denmark at the time of their isolation.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacteriophage Typing
  • Denmark
  • Drug Resistance, Microbial
  • Drug Utilization
  • Fusidic Acid / pharmacology*
  • Genes, Bacterial
  • Humans
  • Microbial Sensitivity Tests
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / genetics

Substances

  • Anti-Bacterial Agents
  • Fusidic Acid