Abstract
We performed a retrospective extended-spectrum β-lactamase (ESBL) molecular characterization of Proteus mirabilis isolates recovered from urine of spinal cord injury patients. A incorrectly detected TEM-24-producing clone and a new weakly expressed TEM-derived ESBL were discovered. In such patients, ESBL detection in daily practice should be improved by systematic use of a synergy test in strains of P. mirabilis resistant to penicillins.
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacteriuria / epidemiology*
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Bacteriuria / microbiology
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Cluster Analysis
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Disease Outbreaks*
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Genotype
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Humans
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Penicillins / pharmacology
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Proteus Infections / epidemiology*
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Proteus Infections / microbiology
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Proteus mirabilis / classification
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Proteus mirabilis / enzymology*
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Proteus mirabilis / genetics
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Proteus mirabilis / isolation & purification*
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Recurrence
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Retrospective Studies
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Spinal Cord Injuries / complications*
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Urine / microbiology
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beta-Lactam Resistance
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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Penicillins
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beta-Lactamases