Abstract
Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.
MeSH terms
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Acetylgalactosamine / chemistry
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Animals
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Antiprotozoal Agents / pharmacology*
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Carbohydrate Conformation
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Carbohydrate Sequence
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Cell Wall / drug effects
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Chemistry, Pharmaceutical / methods*
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Drug Design
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Giardia / metabolism*
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Humans
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Models, Chemical
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Molecular Sequence Data
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Nucleotides / chemistry*
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Trophozoites
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Water / chemistry
Substances
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Antiprotozoal Agents
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Nucleotides
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Water
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Acetylgalactosamine