Cephalosporins can be prescribed safely for penicillin-allergic patients

J Fam Pract. 2006 Feb;55(2):106-12.

Abstract

The widely quoted cross-allergy risk of 10% between penicillin and cephalosporins is a myth. Cephalothin, cephalexin, cefadroxil, and cefazolin confer an increased risk of allergic reaction among patients with penicillin allergy. Cefprozil, cefuroxime, cefpodoxime, ceftazidime, and ceftriaxone do not increase risk of an allergic reaction.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Cephalosporins / therapeutic use*
  • Cross Reactions
  • Drug Hypersensitivity / etiology
  • Drug Hypersensitivity / prevention & control*
  • Drug Prescriptions*
  • Humans
  • Penicillins / adverse effects*
  • Risk Factors

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Penicillins