blaVIM-7, an evolutionarily distinct metallo-beta-lactamase gene in a Pseudomonas aeruginosa isolate from the United States

Antimicrob Agents Chemother. 2004 Jan;48(1):329-32. doi: 10.1128/AAC.48.1.329-332.2004.

Abstract

As part of the CANCER Antimicrobial Surveillance Program in North America, a Pseudomonas aeruginosa isolate, strain 07-406, was shown to possess a metallo-beta-lactamase, designated VIM-7. bla(VIM-7) is located on a 24-kb plasmid which can be readily transferred into Enterobacteriaceae and other pseudomonads. This is the first report of a mobile metallo-beta-lactamase gene, bla(VIM-7), being detected within the United States.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Cloning, Molecular
  • Escherichia coli / genetics
  • Escherichia coli / metabolism
  • Female
  • Humans
  • Middle Aged
  • Molecular Sequence Data
  • Phylogeny
  • Plasmids / genetics
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa / enzymology*
  • Pseudomonas aeruginosa / genetics*
  • United States
  • beta-Lactamases / genetics*

Substances

  • VIM-7 metallo-beta-lactamase
  • beta-Lactamases

Associated data

  • GENBANK/AJ536835