Abstract
Gram-positive bacterial meningitis frequently complicates ventriculo-peritoneal (VP) shunts used for hydrocephalus. Linezolid, an oxazolidinone, is active against Gram-positive cocci, and has excellent CSF penetration. We present a 22-year-old woman who was cured of a Staphylococcus epidermidis VP shunt infection via shunt removal and intravenous linezolid.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Acetamides / therapeutic use*
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Adult
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Anti-Bacterial Agents / therapeutic use*
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Device Removal
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Female
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Humans
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Linezolid
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Meningitis, Bacterial / drug therapy*
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Meningitis, Bacterial / microbiology
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Meningitis, Bacterial / therapy
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Oxazolidinones / therapeutic use*
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Staphylococcal Infections / drug therapy*
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Staphylococcal Infections / therapy
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Staphylococcus epidermidis*
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Ventriculoperitoneal Shunt*
Substances
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Acetamides
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Anti-Bacterial Agents
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Oxazolidinones
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Linezolid