A 1998 survey of extended-spectrum beta-lactamases in Enterobacteriaceae in France. The French Study Group

Antimicrob Agents Chemother. 2000 Nov;44(11):3177-9. doi: 10.1128/AAC.44.11.3177-3179.2000.

Abstract

In a 3-month period in 1998, 79 consecutive isolates of Enterobacteriaceae producing an extended-spectrum beta-lactamase (ESBL) were collected. ESBLs were predominantly TEM derivatives (74 of 79): TEM-24-like (40 isolates), TEM-3-like (29 isolates), TEM-21 (3 isolates), and TEM-4 and TEM-52 (1 isolate each). Four isolates produced SHV derivatives SHV-4 (three isolates) and SHV-5 (one isolate), and one strain produced a CTX-M-3 enzyme. The high proportion of TEM-24-like-producing Enterobacter aerogenes isolates (36 of 79) suggests the occurrence of an epidemic strain in France.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Data Collection
  • Enterobacteriaceae / enzymology*
  • France
  • Humans
  • beta-Lactamases / metabolism*

Substances

  • beta-Lactamases