Table 1. Broth dilution minimum inhibitory concentrations (ug/ml) (Ref 20, 10, 26, 17, 18)
|
MIC (ug/ml) (Lightfoot) |
MIC (ug/ml) (Doganay) |
MIC (ug/ml) (CDC) |
MIC (ug/ml) (USAMRIID) |
||||||||
ANTIBIOTIC |
Range |
MIC50 |
MIC90 |
Range |
MIC50 |
MIC90 |
Range |
MIC50 |
MIC90 |
Range |
MIC50 |
MIC90 |
Amikacin |
|
|
|
0.03-0.06 |
0.03 |
0.06 |
|
|
|
1-4 |
2 |
2 |
Gentamicin |
0.06-0.5 |
0.125 |
0.25 |
0.03-0.25 |
0.06 |
0.125 |
|
|
|
1-4 |
2 |
2 |
Netilmicin |
|
|
|
0.015-0.125 |
0.06 |
0.125 |
|
|
|
2-8 |
2 |
4 |
Streptomycin |
0.5-4 |
1 |
1 |
1-4 |
2 |
4 |
|
|
|
4-16 |
4 |
8 |
Tobramycin |
|
|
|
0.25-1 |
0.25 |
1 |
|
|
|
1-16 |
2 |
4 |
Vancomycin |
|
|
|
0.25-1 |
1 |
1 |
0.5-2 |
2 |
2 |
1-4 |
2 |
2 |
Oritavancin |
|
|
|
|
|
|
|
|
|
<0.03-1 |
0.25 |
0.5 |
Erythromycin |
0.25-1 |
0.5 |
1 |
0.25-1 |
0.5 |
1 |
0.5-1 |
1 |
1 |
|
|
|
Azithromycin |
|
|
|
0.5-4 |
1 |
4 |
|
|
|
2-32 |
8 |
8 |
Clarithromycin |
|
|
|
0.03-0.25 |
0.06 |
0.12 |
|
|
|
0.25-2 |
0.5 |
1 |
Clindamycin |
|
|
|
0.5-1 |
1 |
1 |
<0.5-1 |
<0.5 |
1 |
0.12-1 |
0.25 |
0.5 |
Levofloxacin |
|
|
|
|
|
|
|
|
|
0.06-1 |
0.25 |
0.5 |
Ofloxacin |
|
|
|
0.03-0.06 |
0.06 |
0.06 |
|
|
|
0.25-2 |
1 |
2 |
Ciprofloxacin |
0.03-0.06 |
0.06 |
0.06 |
0.03-0.06 |
0.03 |
0.06 |
0.03-0.12 |
0.06 |
0.06 |
0.06-2 |
0.25 |
1 |
Sparfloxacin |
|
|
|
|
|
|
|
|
|
0.12-2 |
0.5 |
0.5 |
Novobiocin |
|
|
|
|
|
|
|
|
|
1-4 |
2 |
2 |
Amox/clav (2:1) |
|
|
|
0.015-0.015 |
0.015 |
0.015 |
|
|
|
0.5-16 |
1 |
2 |
Amoxicillin |
0.03-64 |
0.06 |
0.125 |
0.015-0.03 |
0.015 |
0.015 |
|
|
|
8->64 |
64 |
>64 |
Ampicillin |
|
|
|
0.03-0.125 |
0.03 |
0.03 |
|
|
|
4->64 |
64 |
>64 |
Penicillin G |
0.015-64 |
0.06 |
0.125 |
0.015-0.03 |
0.015. |
0.015 |
<0.06-128 |
<0.06 |
<0.06 |
2->64 |
64 |
>64 |
Piperacillin |
|
|
|
0.125-0.5 |
0.25 |
0.5 |
|
|
|
16->64 |
64 |
>64 |
Imipenem |
|
|
|
|
|
|
|
|
|
<0.03->64 |
<0.03 |
0.12 |
Meropenem |
|
|
|
|
|
|
|
|
|
<0.03->64 |
0.06 |
0.12 |
Ceftazidime |
|
|
|
128-256 |
128 |
256 |
|
|
|
>64 |
>64 |
>64 |
Cefotaxime |
|
|
|
8-32 |
32 |
32 |
|
|
|
16->64 |
32 |
>64 |
Cefotetan |
|
|
|
|
|
|
|
|
|
8-32 |
16 |
16 |
Cefuroxime |
1-64 |
32 |
64 |
16-64 |
64 |
64 |
|
|
|
16->64 |
64 |
>64 |
Cefazolin |
|
|
|
0.015-0.03 |
0.015 |
0.015 |
|
|
|
0.5-8 |
0.5 |
1 |
Ceftriaxone |
|
|
|
16-32 |
16 |
32 |
14-32 |
16 |
32 |
16->64 |
16 |
64 |
Aztreonam |
|
|
|
>128 |
>128 |
>128 |
|
|
|
>64 |
>64 |
>64 |
Sulfamethoxazole |
|
|
|
|
|
|
|
|
|
2->64 |
>64 |
>64 |
Co-trimoxazole |
|
|
|
8-16 |
16 |
16 |
|
|
|
2->64 |
>64 |
>64 |
Trimethoprim |
|
|
|
|
|
|
|
|
|
>64 |
>64 |
>64 |
Tetracycline |
0.06-1.0 |
0.125 |
0.125 |
|
|
|
0.03-0.06 |
0.03 |
0.06 |
|
|
|
Doxycycline |
|
|
|
|
|
|
|
|
|
<0.03-0.12 |
0.06 |
0.06 |
Tigecycline |
|
|
|
|
|
|
|
|
|
<0.03-0.5 |
0.12 |
0.5 |
Clofazamine |
|
|
|
|
|
|
|
|
|
8-64 |
16 |
32 |
Rifampin |
|
|
|
|
|
|
<0.25-0.5 |
<0.25 |
0.5 |
<0.03-1 |
0.5 |
0.5 |
Quinupristin-Dalfopristin |
|
|
|
|
|
|
|
|
|
0.25-4 |
1 |
1 |
Chloramphenicol |
2-4 |
4 |
4 |
1-2 |
2 |
2 |
2-8 |
4 |
4 |
8-64 |
16 |
16 |
Daptomycin |
|
|
|
|
|
|
|
|
|
1-4 |
2 |
2 |
Linezolid |
|
|
|
|
|
|
|
|
|
1-4 |
2 |
4 |