Table 1. In-Vitro Susceptibilities of the Coagulase-Negative Staphylococci
Antimicrobial
No. of
Isolates
Susceptibility (mg / ml)
Class
Drug
MIC50
MIC90
Range
Fluoroquinolones
Ciprofloxacin
163
0.25
0.5
0.06 - 32
Norfloxacin
145
2
0.12 - 64
Ofloxacin
139
1
Sparfloxacin
69
0.12
0.12 - 8
Levofloxacin
58
4
0.25 - 32
<0.06 - 4
Gatifloxacin
41
0.06 - 8
Aminoglycosides
Gentamicin
18
0.03
16
0.015 - 32
Tobramycin
158
<0.25
>16
<0.25 - > 16
Netilmicin
0.125
0.03 - 4
MLS antibiotics
Erythromycin
150
≥64
0.125 - ≥64
Clindamycin
14
0.06
<0.06 - ≥64
Quinupristin / dalfopristin
202
0.25 - 1
β-lactams
Penicillin
126
64
<0.06 - 64
Amoxicillin /clavulanate
102
≤ 0.015 - 2
Cephalexin
60
Cefuroxime
95
0.25 - 128
Ceftriaxone
160
Cefixime
81
> 64
0.06 - > 64
Imipenem
277
0.016 - 2
Meropenem
319
8
0.0075 - 8
Others
789
0.25 - 4
Doxycycline
0.06 - 16
Vancomycin
325
Teicoplanin
231
Trimethoprim
20
0.12 - 4
*TMP / SMX
117
Rifampin
45
0.008
0.016
< 0.002 - 0.03
Fusidic acid
NS**
0.064 - 32
*Trimethoprim-sulfamethoxazole
**Not stated