*Table 1. In Vitro* Susceptibilities of Plesiomonas shigelloides^a**

Antibiotic	n	Range			MIC₅₀		MIC₉₀			Breakpoint^b	% Susceptible		Reference
Amdinocillin	4	£0.5-32			£0.5		1						8
Amoxicillin	29	0.06-³64			64		³128		£8			7	11
Amoxicillin	14	1->32			>32		>32		£8				2
Amoxicillin	52	4-256			128		256		£8			2	53
Amoxicillin-clavulanate	29	£0.06/0.03-8/4			2/1			4/2	£8/4			100	11
Ampicillin	17	2-32			8		16			£8			48
Ampicillin	72	32-³256			128			256	£8			0	30
Ampicillin	29	0.25-³128			³128			³128	£8			3	11
Ampicillin	4	8-32			8			8	£8				8
Ampicillin-sulbactam	29	0.25/0.12-4/2			1/0.5			2/1	£8/4			100	11
Azlocillin	74	4-1024			1024			1024					53
Benzylpenicillin	74	0.25-64			64			64					53
Oxacillin	52	32-128			128			128					53
Piperacillin	72	8-³256			³256			³256	£16			3	30
Piperacillin	29	£0.06-³64			64			³128	£16			7	11
Piperacillin	74	4-512			512			512	£16			1	53
Piperacillin-tazobactam	29	£0.06/0.0075-1/0.125			0.25/0.03			1/0.125	£16/4			100	11
Ticarcillin	72	64-³128			³128			³128	£16			0	30
Ticarcillin	29	0.5-³128			³128			³128	£16			4	11
Ticarcillin	74	16-512			512			512	£16			1	53
Ticarcillin-clavulanate	29	0.5/2-4/2			1/2			2/2	£16/2			100	11
Mezlocillin	29	0.125-³128			³128			³128	£16			14	11
Mezlocillin	74	0.13-512			512			512	£16			1	53
Carbenicillin	72	128-³512			256			512	£16			0	30
Cefaclor	14	0.5-4			1			1	£8			100	2
Cefaclor	52	0.13-16			2			8	£8			96	53
Cefamandole	72	£1-4			£1			£1	£8			100	30
Cefamandole	29	£0.06-0.5			£0.06			0.25	£8			100	11
Cefazolin	72	£1-8			£1			£1	£8			100	30
Cefazolin	74	1-4			2			2	£8			100	53
Cefdinir	52	0.03-2			1			2	£1			81	53
Cefepime	52	0.03-32			16			32	£8			46	53
Cefetamet	14	£0.06-0.12			£0.06		0.12						2
Cefetamet	52	0.03-4			2		4		£4			100	53
Cefixime	52	0.03-4			1		2		£1			62	53
Cefoperazone	72	£1-8			£1			£1	£16			100	30
Cefoperazone	29	£0.06-8			1			4	£16			100	11
Cefoperazone	52	1-128			32			64	£16			44	53
Cefoperazone-sulbactam	29	£0.06/0.03-0.5/0.25			0.125/0.06			0.25/0.125	£16/8			100	11
Cefotaxime	17	£0.063-0.125			£0.063			£0.063		£8		100	48
Cefotaxime	72	£8			£8			£8	£8			100	30
Cefotaxime	29	£0.06-4			£0.06			£0.06	£8			100	11
Cefotaxime	52	0.03-8			1			2	£8			100	53
Cefoxitin	72	£4			£4			£4	£8			100	30
Cefoxitin	29	1-4			2			4	£8			100	11
Cefoxitin	74	2-16			4			8	£8			93	53
Cefpodoxime	52	0.03-4			2			4	£2			88	53
Ceftazidime	72	£1			£1			£1	£8			100	30
Ceftazidime	29	£0.06-1			£0.06			£0.06	£8			100	11
Ceftazidime	52	0.03-64			16			32	£8			19	53
Ceftriaxone	72	£1			£1			£1	£8			100	30
Ceftriaxone	29	£0.06			£0.06			£0.06	£8			100	11
Ceftriaxone	52	0.03-1			0.25			0.5	£8			100	53
Cefuroxime	29	£0.06-0.125			£0.06			£0.06	£8			100	11
Cefuroxime	52	0.03-4			2			4	£8			100	53
Cephalexin	14	2-16			4			8					2
Cephalothin	72	£8			£8			£8	£8			100	30
Cephalothin	29	0.5-2			1			2	£8			100	11
Loracarbef	52	0.25-16			8			8	£8			90	53
Aztreonam	29	£0.06			£0.06			£0.06	£8			100	11
Aztreonam	52	0.03-32			8			16	£8			62	53
Imipenem	29	£0.06-0.25			£0.06			0.125	£4			100	11
Imipenem	74	0.03-0.25			0.13			0.25	£4			100	53
Meropenem	74	0.03-0.25			0.03			0.13	£4			100	53
Chloramphenicol	17	0.25-8			0.5		1			£8		100	48
Chloramphenicol	72	£4	£4			£4			£8			100	30
Chloramphenicol	74	0.25-1	0.5			0.5			£8			100	53
Teicoplanin	74	64-256	256			256							53
Vancomycin	74	16-128	128			128							53
Ciprofloxacin	17	£0.063	£0.063			£0.063			£1			100	48
Ciprofloxacin	72	£1	£1			£1			£1			100	30
Ciprofloxacin	29	£0.06		£0.06		£0.06			£1			100	11
Ciprofloxacin	<19	<0.001-0.015		0.004		0.008			£1			100	4
Ciprofloxacin	13	£0.06		£0.06		£0.06			£1			100	26
Ciprofloxacin	74	0.01-0.25		0.01		0.01			£1			100	53
Enoxacin	17	£0.063-0.25		£0.063		0.125			£2			100	48
Enoxacin	4	£0.5		£0.5		£0.5			£2			100	8
Enoxacin	<19	0.03-0.125		0.06		0.125			£2			100	4
Enoxacin	74	0.01-8		0.03		0.03			£2			99	53
Fleroxacin	74	0.01-4		0.01		0.03			£2			99	53
Norfloxacin	17	£0.063-0.125	£0.063			£0.063							48
Norfloxacin	72	£0.1-1	£0.1			£0.1							30
Norfloxacin	4	£0.5		£0.5		£0.5							8
Norfloxacin	<19	<0.015-0.06		0.03		0.06							4
Norfloxacin	74	0.03-2		0.03		0.03			£4			100	53
Ofloxacin	<19	0.008-0.03		0.015		0.015			£2			100	4
Ofloxacin	74	0.01-1		0.01		0.01			£2			100	53
Pefloxacin	<19	<0.015-0.06		0.015		0.06							4
Pefloxacin	74	0.01-8		0.01		0.01							53
Sparfloxacin	74	0.01-0.25		0.01		0.01							53
Pipemidic acid	<19	0.125-0.5		0.125		0.25							4
Pipemidic acid	74	0.5-64		1		1							53
Azithromycin	74	0.06-4		0.5		1							53
Clarithromycin	74	2-64		16		32							53
Erythromycin	72	4-32	16			16			£0.5			0	30
Erythromycin	4	16-32		32		32			£0.5			0	8
Erythromycin	13	0.5-14		1		4			£0.5				26
Erthromycin	74	1-32		8		32			£0.5			0	53
Roxithromycin	74	2-64		16		64							53
Clindamycin	74	4-64		32		64							53
Lincomycin	74	32-64		64		64							53
Furazolidone	4	£0.5		£0.5		£0.5							8
Amikacin	72	8-64	16			32			£16			54	30
Amikacin	29	£0.06-16	0.25			8			£16			100	11
Amikacin	74	1-64	16			32			£16			81	53
Gentamicin	17	2-8	4			8			£4				48
Gentamicin	72	4-16	4			6			£8			57	30
Gentamicin	29	1-8	4			8			£4			86	11
Gentamicin	13	2-12	3			10			£4				26
Gentamicin	74	0.5-8	2			4			£4			95	53
Tobramycin	72	4-8	4			6			£4			36	30
Tobramycin	29	£0.06-8	£0.06			1			£4			97	11
Tobramycin	74	0.5-8	2			4			£4			93	53
Kanamycin	13	0.4-10	0.6			8			£16			100	26
Kanamycin	74	2-32	8			32			£16			88	53
Neomycin	74	1-16	4			8							53
Netilmicin	72	2-4	4			4			£8			100	30
Netilmicin	74	0.5-16	2			4			£8			99	53
Streptomycin	74	4-64	16			32							53
Spectinomycin	74	2-32	16			32							53
Apramycin	52	4-128	32			64							53
Ribostamycin	74	1-64	16			32							53
Lividomycin A	74	4-128	32			64							53
Nalidixic acid	17	0.25-2	0.5			0.5							48
Nalidixic acid	<19	0.5-2	1			2							4
Doxycycline	4	£0.5	£0.5			£0.5			£4			100	8
Doxycycline	74	0.06-2	0.25			0.25			£4			100	53
Tetracycline	17	0.25-2	0.5			0.5			£4			100	48
Tetracycline	72	£1-64	³1			32			£4			68	30
Tetracycline	13	0.25-2.4		0.5		1			£4			100	26
Tetracycline	74	0.13-8		0.25		0.5			£4			99	53
Minocycline	74	0.03-0.5		0.13		0.25			£4			100	53
Trimethoprim-sulphamethoxazole^c	17	£0.063-0.125		0.125		0.125			£2/38			100	48
Trimethoprim-sulphamethoxazole	72	£0.1-0.5		£0.1		0.5			£2/38			100	30
Trimethoprim-sulphamethoxazole	4	0.05		0.05		0.05			£2/38			100	8
Trimethoprim-sulphamethoxazole	74	1-256		2		16			£2/38			53	53
Trimethoprim	17	0.25-4		1		4							48
Trimethoprim	72	£1		£1		£1			£8			100	30
Trimethoprim	4	£0.5-2		£0.5		£0.5							8
Trimethoprim	74	0.13-64		1		8			£8			93	53
Sulfisoxazole	72	£32-³512		32		256							30
Sulphamethoxazole	17	4.75-19		9.5		19							48
Sulphamethoxazole	74	16-1024		1024		1024							53
Nitrofurantoin	74	2-64		8		8			£32			99	53
Rifampicin	74	0.25-64		4		8							53
Bicozamycin	4	16		16		16							8
Telithromycin	11	4-8		4		4							19
Fosfomycin	74	0.5-256		32		64			£64			92	53
Fusidic acid	74	4-64		64		64							53
Dalfopristin	74	4-128		32		64							53
Quinupristin	74	64-128		128		128							53
Dalfopristin/quinupristin	74	4-64		32		32							53

^a Modified from (2, 4, 8, 11, 26, 30, 48, 53).^b Current CLSI interpretive standards for susceptibility of Enterobacteriaceae (µg/ml) (42)^c Trimethoprim-sulphamethoxazole tested in a ratio of 1:19. The concentration refers to the trimethoprim component.