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Legionella species (Legionnaires’ disease)

 

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Sliding Table of Contents on the left of the screen

 

Tables and Figures

Table 1: Susceptibility of Legionella spp. To Antimicrobial Agents by In Vitro Agar Dilution Method. 

Table 2: Susceptibility of Legionella spp. To Antimicrobial Agents by In Vitro Broth Dilution Method

Table 3: Activity of Antimicrobial Agents Using In Vivo Animal Model 

Table 4: Antibiotic Doses for Legionella Infection 

 

Vignettes

Review Article: Sabria M, Yu VL. Hospital-acquired Legionellosis: Solution for a preventable infection. The Lancet Infectious Diseases, 2:368-373, June 2002.

Review Article:  Adhikari P, Mietzner T.  Cell Mediated Immunity. 2008.

Review Article: Greenberg D, Chiou CC, et al.  Problem pathogens: paediatric legionellosis-implications for improved diagnosis.  Lancet Infect Dis 2006;6:529-535.

Review Article:  Pedro-Botet ML, et al.  Legionnaires' Disease contracted from patient homes: the coming of the third plague?  Eur J Clin Microbiol Infect Dis 2002;21(10):699-705.

Review Article: Neil K, Berkelman R. Increasing Incidence of Legionellosis in the United States, 1990-2005: Changing Epidemiologic Trends.Clin Infect Dis. 2008 Sep 1;47(5):591-9.

Review Article:  Pedro-Botet ML, et al.  Treatment strategies for Legionella Infection.  Expert Opin Pharmacother 2009;10:1109-1121.

Berger S.  Emergence of Infectious Diseases into the 21st Century, 2008.

Yu VL, Stout JE.  Community-Acquired Legionnaires' Disease: Implications for Underdiagnosis and Laboratory Testing. Clin Infect Dis 2008;46:1365-1367.

Stout JE, Muder RR.  Role of Environmental Surveillance in Determining the Risk of Hospital-Acquired Legionellosis: A National Surveillance Study with Clinical Correlations.  Infect Control Hosp Epidemiol 2007;28:818-824.

Seenivasan MH, Yu VL, et al.  Legionnaires' Disease in Long-Term Care Facilities: Overview and Proposed Solutions.  JAGS 2005;53:875-880.

Griffin AT, et al. Macrolides versus quinolones in Legionella pneumonia: results from the Community-Acquired Pneumonia Organization international study. Int J Tuberc Lung Dis. 2010 Apr;14:495-9.

Gudiol C, Verdaguer R, et al. Outbreak of Legionnaires' Disease in Immunosuppressed Patients at a Cancer Centre: Usefulness of Universal Urine Antigen Testing and Early Levofloxacin Therapy. Clin Microbiol Infect. 2007 Nov;13:1125-8.

Neil K, et al. Increasing Incidence of Legionellosis in the United States, 1990-2005: Changing Epidemiologic Trends. Clin Infect Dis. 2008 Sep 1;47:591-9.

Patel MC, et al. L. micdadei PVE Successfully Treated with Levofloxacin/Valve Replacement: Case Report and Review of the Literature. J Infect. 2005 Dec;51:e265-8.
Ng V, et al. Our Evolving Understanding of Legionellosis Epidemiology: Learning to Count. Clin Infect Dis. 2008 Sep 1;47:600-2.

Yu VL, Greenberg RN, et al. Levofloxacin Efficacy in the Treatment of Community-Acquired Legionellosis.  Chest 2004;125 (6):2135-2139.

Stout JE.  Preventing Legionellosis.  ASHRAE Journal. 2007:58-62.

Stout JE, Yu VL.  Experience of the First 16 Hospitals Using Copper-Silver Ionization for Legionellosis Control: Implications for the Evaluation of Other Disinfection Modalities.  Infect Control Hosp Epidemiol 2003;24 (8):563-568.

Pedro-Botet L, et al.  Legionella: macrolides or quinolones. Clin Microbiol Infect 2006;12 (Suppl 3):25-30.

 

Authors

Miguel Sabria, M.D.,  Victor L. Yu, M.D. M. Luisa Pedro-Botet  Yu-Sen Eason Lin

First Edition (1998): Emanuel N. Vergis and Victor L. Yu

 

 

 

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