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Pseudomonas aeruginosa

 

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Sliding Table of Contents on the left of the screen

 

Tables and Figures

Table 1: Minimum Inhibitory Concentrations of P. aeruginosa for Selected Antibiotics 

Table 2: Drug of Choice [Total Daily Dose (Dosing Interval in Hours)]

Table 3: Special Infections [Total Daily Dose (Dosing Interval in Hours)]

Table 4: Doses of IV Aminoglycosides in Specific Infections [Total Daily Dose (Dosing Interval in Hours)]

Table 5: Recommended Dosages of Antimicrobial Agents Given by the Intraventricular Route

 

Vignettes

Review Article: Golnaz J, Zuravleff J.  Retinitis and Endophthalmitis. 2007.

Review Article: Grandis JR, Branstetter BF, Yu VL. The changing face of malignant (necrotising) external otitis: clinical, radiological, and anatomic correlations. Lancet Infect Dis 2004;4:34-39.

Review Article: Hoiby N. P. aeruginosa in Cystic Fibrosis Patients Resists Host Defenses, Antibiotics.  Microbe 2006;12:571-577.

Review Article:  Javey G, Zuravleff J.  Keratitis. 2007.

Review Article: Leid, JG. Bacterial Biofilms Resist Key Host Defenses. Microbe/Volume 4, Number 2, 2009.

Review Article: O'Toole GA.  How Pseudomonas aeruginosa regulates surface behaviors. Microbe 2008;3:65-71.

Review Article: Poole K. Bacterial Multidrug Efflux Pumps Serve Other Functions. Microbe 2008;3:179-185.

Review Article:  Efflux Pumps as a Mechanism of Antimicrobial Resistance. 2008

Review Article: Raad I, Hanna H, and Maki D. Intravascular Catheter-related Infections: Advances in Diagnosis, Prevention and Management. The LANCET Infectious Diseases

2007;7:645-657. 

Review Article: Safdar N, Handelsman J, Maki DG. Does combination antimicrobial therapy reduce mortality in Gram-negative bacteraemia? A meta-analysis. Lancet Infect Dis. 2004;4(8): 519-27.

Review Article:  Tabibian JH, et al.  Uropathogens and Host Characteristics. J Clin Microbiol 2008;46:3980-3986.

Martinez-Solano L et al. Chronic Pseudomonas aeruginosa Infection in Chronic Obstructive Pulmonary Disease. Clin Infect Dis. 2008;47(12):1526-33.

Dohar, JE et al. Differences in Bacteriologic Treatment Failures in Acute Otitis Externa Between Ciprofloxacin/Dexamethasone and Neomycin/Polymyxin B/Hydrocortisone: Results of a Combined Analysis.  Curr Med Res Opin. 2009;25(2):287-91.

Goldstein EJ, Citron DM, et al. Introduction of Ertapenem into a Hospital Formulary: Effect on Antimicrobial Usage and Improved in vitro Susceptibility of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2009;53:5122-6.

King P, Lomovskaya O, et al. In vitro Pharmacodynamics of Levofloxacin and Other Aerosolized Antibiotics Under Multiple Conditions Relevant to Chronic Pulmonary Infection in Cystic Fibrosis. Antimicrob Agents Chemother. 2010;54:143-8.

Kusne S, Eibling DE, et al. Gangrenous Cellulitis Associated with Gram-Negative Bacilli in Pancytopenic Patients. Am J Med. 1988;85:490-4.

Schechner V, et al. Gram-negative Bacteremia upon Hospital Admission: When Should Pseudomonas aeruginosa be Suspected?  Clin Infect Dis. 2009;48:580-6.

Tam VH et al. Outcomes of Bacteremia due to Pseudomonas aeruginosa with Reduced Susceptibility to Piperacillin-Tazobactam: Implications on the Appropriateness of the Resistance Breakpoint.  Clin Infect Dis. 2008;46:862-7.

 

Authors

 

Shigeki Fujitani, M.D, Kathryn S. Moffett, M.D., David L. Paterson, M.D.

 

Second Edition: Ashish Acharya, M.D., David L. Paterson, M.D.

First Edition (1998): Victor L. Yu and David L. Paterson

 

 

 

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